Description

3-Fluoro-2-Formyl-4-Methoxyphenylboronic Acid is a highly functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a fluorinated methoxyphenyl core, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients through cross-coupling reactions and other advanced synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and infectious diseases via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom and boronic acid group contribute to enhanced biological activity and metabolic stability.
• Material Science: Employed in the creation of advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, where its electronic properties can be finely tuned.
• Chemical Synthesis Reagent: Serves as a versatile building block in organic synthesis for constructing complex biaryl and heterobiaryl structures common in many specialty chemicals.
• Diagnostic Probe Development: Utilized in the design and synthesis of molecular probes and sensors for biochemical assays and diagnostic applications.

Basic Information

Product Name	3-Fluoro-2-Formyl-4-Methoxyphenylboronic Acid
CAS No.	1451392-03-2
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	(3-Fluoro-2-formyl-4-methoxyphenyl)boronic acid; 2-Formyl-3-fluoro-4-methoxybenzeneboronic acid; 3-Fluoro-2-formyl-4-methoxybenzeneboronic acid; Boronic acid, B-(3-fluoro-2-formyl-4-methoxyphenyl)-; 3-Fluoro-4-methoxy-2-formylphenylboronic acid; CAS 1451392-03-2
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Formyl-4-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.