Description

4-Fluoro-3-Methoxy-5-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated and methoxylated aromatic scaffolds.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where its specific substitution pattern imparts desired electronic or physical properties.
• Chemical Biology Probes: Useful in constructing molecular probes and tags for studying biological processes due to its biocompatible coupling chemistry.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the global life sciences industry.

Basic Information

Product Name	4-Fluoro-3-Methoxy-5-Methylphenylboronic Acid
CAS No.	1451392-02-1
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(4-Fluoro-3-methoxy-5-methylphenyl)boronic acid; 4-Fluoro-3-methoxy-5-methylbenzeneboronic acid; 3-Methoxy-5-methyl-4-fluorophenylboronic acid; Boronic acid, B-(4-fluoro-3-methoxy-5-methylphenyl)-; 1451392-02-1; 4-Fluoro-3-methoxy-5-methyl-phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3-Methoxy-5-Methylphenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.