Description

2-Fluoro-3-Methoxypyridin-4-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through metal-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals. Its specific substitution pattern on the pyridine ring makes it a valuable synthon for creating targeted molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting the central nervous system, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other advanced materials.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and inhibitors for studying enzyme function and protein-protein interactions.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling to form carbon-carbon bonds, enabling the modular construction of biaryl and heterobiaryl structures.
• Ligand Synthesis: Acts as a starting material for the preparation of specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Fluoro-3-Methoxypyridin-4-Ylboronic Acid
CAS No.	1451392-01-0
Molecular Formula	C6H7BFNO3
Molecular Weight	170.94 g/mol
Synonyms	(2-Fluoro-3-methoxypyridin-4-yl)boronic Acid; 2-Fluoro-3-methoxy-4-pyridineboronic Acid; 4-Borono-2-fluoro-3-methoxypyridine; 2-Fluoro-3-methoxy-4-pyridinylboronic Acid; 2-Fluoro-3-methoxypyridine-4-boronic Acid; 1451392-01-0; 2-Fluoro-3-methoxy-4-pyridylboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxypyridin-4-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. For long-term storage, consider storing under an inert gas in a freezer (-20°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.