Description

3-Fluoro-4-Methoxy-5-Trifluoromethylphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials used in displays and lighting.
• Polymer Chemistry: Incorporated into specialty polymers and resins to impart specific chemical or physical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new synthetic pathways and creating complex boronic acid-based libraries.
• Sensor Development: Utilized in the synthesis of molecular recognition elements for chemical and biological sensors due to its boronic acid functionality.

Basic Information

Product Name	3-Fluoro-4-Methoxy-5-Trifluoromethylphenylboronic Acid
CAS No.	1451391-99-3
Molecular Formula	C9H7BF4O3
Molecular Weight	250.96 g/mol
Synonyms	(3-Fluoro-4-methoxy-5-(trifluoromethyl)phenyl)boronic acid; 3-Fluoro-4-methoxy-5-trifluoromethylbenzeneboronic acid; 5-Trifluoromethyl-3-fluoro-4-methoxyphenylboronic Acid; Boronic acid, B-[3-fluoro-4-methoxy-5-(trifluoromethyl)phenyl]-; 1451391-99-3; 3-Fluoro-4-methoxy-α,α,α-trifluoromethylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Methoxy-5-Trifluoromethylphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.