Description

6-Fluoro-2-Methoxy-3-Methylphenylboronic Acid is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures via cross-coupling reactions. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine and methoxy substituents for enhanced biological activity.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Catalyst & Ligand Development: Used to synthesize novel ligands for transition metal catalysts used in fine chemical manufacturing.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects requiring specific aryl boronic acid derivatives.

Basic Information

Product Name	6-Fluoro-2-Methoxy-3-Methylphenylboronic Acid
CAS No.	1451391-96-0
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(6-Fluoro-2-methoxy-3-methylphenyl)boronic acid; 2-Methoxy-6-fluoro-3-methylbenzeneboronic acid; 3-Methyl-6-fluoro-2-methoxybenzeneboronic acid; Boronic acid, B-(6-fluoro-2-methoxy-3-methylphenyl)-; 1451391-96-0; 6-Fluoro-2-methoxy-3-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Methoxy-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.