Description

3-(4-Bromo-3-Fluorophenyl)Cyclobutanecarboxylic Acid is a high-purity, multifunctional organic building block featuring a cyclobutane core substituted with a halogenated aromatic ring. This compound is valued for its unique steric and electronic properties, making it a critical intermediate in the synthesis of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the halogenated phenyl group.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of specialty polymers or liquid crystals where the rigid cyclobutane structure imparts desired physical properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-(4-Bromo-3-Fluorophenyl)Cyclobutanecarboxylic Acid
CAS No.	1451085-09-8
Molecular Formula	C11H10BrFO2
Molecular Weight	273.10 g/mol
Synonyms	3-(4-Bromo-3-fluorophenyl)cyclobutanecarboxylic acid; 4-Bromo-3-fluorophenylcyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 3-(4-bromo-3-fluorophenyl)-; 1451085-09-8; 3-(4-Bromo-3-fluorophenyl)cyclobutane-1-carboxylic acid; 1-(4-Bromo-3-fluorophenyl)-3-carboxycyclobutane
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Bromo-3-Fluorophenyl)Cyclobutanecarboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.