Description

n-[(1R,2R)-2-[[[[(1S,2S)-2-(Dimethylamino)Cyclohexyl]Amino]Thioxomethyl]Amino]-1,2-Diphenylet is a sophisticated chiral thiourea derivative with a complex stereochemical architecture, making it a valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of high-value, optically active pharmaceuticals and specialty chemicals, where precise stereochemistry is critical for biological activity. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for creating novel therapeutic agents, particularly in areas like enzyme inhibition and receptor targeting.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Asymmetric Catalyst Ligand: Serves as a sophisticated ligand or organocatalyst in enantioselective synthesis, enabling the production of single-isomer compounds.
• Chemical Biology Research: Used as a molecular probe or scaffold in medicinal chemistry for studying protein-ligand interactions and structure-activity relationships (SAR).
• Advanced Material Synthesis: Employed in the development of specialty polymers and functional materials with specific chiral properties.
• Process Chemistry Development: Utilized in route scouting and optimization for the commercial-scale manufacturing of complex drug candidates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory filings in pharmaceutical development.

Basic Information

Item	Detail
Product Name	n-[(1R,2R)-2-[[[[(1S,2S)-2-(Dimethylamino)Cyclohexyl]Amino]Thioxomethyl]Amino]-1,2-Diphenylet
CAS No.	1448608-07-8
Molecular Formula	C23H30N4S
Molecular Weight	394.58 g/mol
Synonyms	(1R,2R)-N-((1S,2S)-2-(Dimethylamino)cyclohexyl)-N'-(1,2-diphenylvinyl)thiourea; (1R,2R)-1,2-Diphenyl-N-(((1S,2S)-2-(dimethylamino)cyclohexyl)carbamothioyl)ethene-1,2-diamine; Chiral Thiourea Derivative; CAS 1448608-07-8; Stereoisomeric Thiourea; (R,R)-(S,S)-DPV-DMACH Thiourea; Asymmetric Thiourea Catalyst; N-[(1R,2R)-2-({[(1S,2S)-2-(Dimethylamino)cyclohexyl]carbamothioyl}amino)-1,2-diphenylethenyl]amine
EINECS	Contact for details

Quality Control

Our n-[(1R,2R)-2-[[[[(1S,2S)-2-(Dimethylamino)Cyclohexyl]Amino]Thioxomethyl]Amino]-1,2-Diphenylet is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard spectroscopic methods for identity confirmation, to ensure high chemical and isomeric purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.