Description

8,12-iso-Ipf2.Alpha.-Vi is a specialized isoprostane analog, a class of prostaglandin-like compounds formed from the free radical-catalyzed peroxidation of arachidonic acid. This compound is of significant value as a high-purity reference standard and a critical biochemical tool for research into oxidative stress and lipid peroxidation pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and diagnostic manufacturers focused on cardiovascular disease, neurodegenerative disorders, and biomarker discovery.

Application

• Biochemical Research Standard: Serves as a certified reference material for the quantification and validation of isoprostane levels in biological samples.
• Oxidative Stress Studies: Used as a precise analytical standard in studies investigating lipid peroxidation and its role in disease mechanisms.
• Diagnostic Assay Development: Essential for the calibration and quality control of ELISA, LC-MS/MS, and other immunoassay kits targeting isoprostane biomarkers.
• Pharmacology & Toxicology: Employed in research to evaluate the efficacy of antioxidants and therapeutic agents that modulate oxidative damage.
• Academic & Institutional Research: A key reagent for fundamental research in biochemistry, cell biology, and molecular medicine related to inflammation and aging.

Basic Information

Product Name	8,12-iso-Ipf2.Alpha.-Vi
CAS No.	1445349-99-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	8,12-iso-iPF2α-VI; 8,12-iso-Isoprostane F2α-VI; 5-F2t-IsoP; 8,12-iso-Prostaglandin F2α type VI; Isoprostane F2α-VI isomer; 8,12-iso-iPF2α-VI; F2-Isoprostane (8,12-iso-iPF2α-VI)
EINECS	Contact for details

Quality Control

Our 8,12-iso-Ipf2.Alpha.-Vi is produced and handled under strict quality management protocols to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, NMR, and MS. We adhere to relevant guidelines for research-grade biochemicals to guarantee reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere if specified and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.