Description

2-Chloro-5-(Pentafluorosulfur)Benzoylchloride is a high-value, multi-functional organofluorine building block characterized by its reactive benzoyl chloride core and pentafluorosulfanyl (SF5) substituent. This compound matters for its ability to introduce both the highly stable, lipophilic SF5 group and an acid chloride moiety into target molecules, enabling the synthesis of advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty materials industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring the metabolically stable and strongly electron-withdrawing pentafluorosulfanyl group.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where the SF5 group can improve bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its derivatives can contribute to desired dielectric, optical, and thermal properties.
• Polymer & Resin Modifier: Employed to functionalize polymers or create specialty monomers, imparting unique characteristics like oil- and water-repellency or enhanced chemical resistance.
• Organic Synthesis Reagent: A versatile reagent for introducing the benzoyl group via amidation or esterification reactions, followed by further elaboration of the SF5-containing aromatic system.
• Ligand & Catalyst Development: Useful in the design of novel ligands for catalysis or metal-organic frameworks (MOFs), leveraging the distinct steric and electronic profile of the SF5 group.

Basic Information

Item	Details
Product Name	2-Chloro-5-(Pentafluorosulfur)Benzoylchloride
CAS No.	1431329-83-7
Molecular Formula	C7H1Cl2F5OS
Molecular Weight	291.04 g/mol
Synonyms	2-Chloro-5-(pentafluoro-λ6-sulfanyl)benzoyl chloride; 5-(Pentafluorosulfanyl)-2-chlorobenzoyl chloride; 2-Chloro-α,α,α,α',α'-pentafluoro-5-(pentafluoro-λ6-sulfanyl)benzenemethanoyl chloride; SF5-Benzoyl Chloride Derivative; Benzoyl chloride, 2-chloro-5-(pentafluorosulfanyl)-; 2-Chloro-5-SF5-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Pentafluorosulfur)Benzoylchloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.