Description

4-Fluoro-3,5-Dimethylcinnamic Acid CAS NO 1429551-15-4 is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic placement of fluorine and methyl groups on the aromatic ring, which allows for precise tuning of electronic and steric properties in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex bioactive scaffolds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display and lighting technologies.
• Polymer Modification: Incorporated into polymer chains to impart specific properties like UV stability, altered refractive index, or specialized surface characteristics.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create diverse biaryl structures.
• Fluorine Chemistry Studies: A model compound for investigating the effects of fluorine substitution on reaction kinetics and molecular conformation.

Basic Information

Product Name	4-Fluoro-3,5-Dimethylcinnamic Acid
CAS No.	1429551-15-4
Molecular Formula	C₁₁H₁₁FO₂
Molecular Weight	194.20 g/mol
Synonyms	(E)-3-(4-Fluoro-3,5-dimethylphenyl)acrylic acid; 3-(4-Fluoro-3,5-dimethylphenyl)-2-propenoic acid; 4-Fluoro-3,5-dimethyl-trans-cinnamic acid; 4-Fluoro-3,5-dimethylcinnamate (acid); F-3,5-DMCA; 4-F-3,5-Dimethyl CA
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-3,5-Dimethylcinnamic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizers, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.