Description

Bay57-1293 Mesylate is a potent and selective small molecule inhibitor of the herpes simplex virus (HSV) helicase-primase complex. This compound is a critical research tool for virologists and pharmaceutical developers targeting novel antiviral therapies. It is primarily utilized in biochemical research, antiviral mechanism of action studies, and the preclinical development pipeline for HSV treatments.

Application

• Antiviral Research & Development: A key reference standard and active pharmaceutical ingredient (API) in the discovery and development of novel herpesvirus treatments.
• Biochemical Assays: Used in in vitro studies to inhibit the HSV helicase-primase enzyme complex, elucidating viral replication mechanisms.
• Virology Studies: Employed in cell-based assays to study HSV infection kinetics, drug resistance, and combination therapy effects.
• Preclinical Pharmacology: Serves as a critical compound in animal model studies to evaluate efficacy, pharmacokinetics, and toxicity profiles of antiviral candidates.
• Pharmaceutical Reference Standard: Used for quality control, method development, and calibration in analytical laboratories.

Basic Information

Product Name	Bay57-1293 Mesylate
CAS No.	1428333-96-3
Molecular Formula	C₂₀H₂₀N₆O₃S • CH₄O₃S
Molecular Weight	528.60 g/mol
Synonyms	N-{5-[(Aminosulfonyl)amino]-1,3,4-thiadiazol-2-yl}-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide methanesulfonate; Bay 57-1293 mesylate; AIC316 mesylate; HSV Helicase-Primase Inhibitor; Pritelivir mesylate (development code)
EINECS	Contact for details

Quality Control

Our Bay57-1293 Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) confirming identity, purity, and specification compliance is provided with every shipment to ensure it meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.