Description

2-Bromo-6-Fluoro-4-Methylbenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromo and fluoro substituents on the methylbenzoic acid core, enabling precise molecular modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the halogenated benzoic acid structure can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals and polymers with specific electronic or optical properties.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Scale-Up: A versatile substrate for contract research organizations (CROs) and custom synthesis providers working on client-specific molecular targets.

Basic Information

Product Name	2-Bromo-6-Fluoro-4-Methylbenzoic Acid
CAS No.	1427327-66-9
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	4-Methyl-2-bromo-6-fluorobenzoic Acid; 6-Fluoro-2-bromo-p-toluic Acid; 2-Bromo-6-fluoro-4-methyl-benzoic acid; Benzoic acid, 2-bromo-6-fluoro-4-methyl-; 4-Methyl-6-fluoro-2-bromobenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Fluoro-4-Methylbenzoic Acid is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research and process development. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.