Description

4-(2,4-Difluorophenyl)Oxane-4-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a difluorophenyl moiety with an oxane carboxylic acid group, enabling precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the creation of advanced polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(2,4-Difluorophenyl)Oxane-4-Carboxylic Acid
CAS No.	1423027-56-8
Molecular Formula	C12H12F2O3
Molecular Weight	242.22 g/mol
Synonyms	4-(2,4-Difluorophenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(2,4-Difluorophenyl)tetrahydropyran-4-carboxylic acid; 2H-Pyran-4-carboxylic acid, 4-(2,4-difluorophenyl)tetrahydro-; 4-(2,4-Difluorophenyl)-4-carboxytetrahydropyran; 4-Carboxy-4-(2,4-difluorophenyl)tetrahydropyran; 4-(2,4-Difluorophenyl)oxane-4-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 4-(2,4-Difluorophenyl)Oxane-4-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.