Description

Apimostinel CAS NO 1421866-48-9 is a high-purity, synthetic pharmaceutical intermediate of significant importance in modern drug development pipelines. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of neurology and metabolic disorders. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the production of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the development and study of potential therapeutics targeting central nervous system disorders.
• Metabolic Disorder Therapeutics: Serves as a building block for compounds under investigation for diabetes and related metabolic conditions.
• Process Chemistry & Scale-up: Employed in process optimization and pilot-scale manufacturing for new drug candidates.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in API production.
• Contract Manufacturing: Supplied to CDMOs for the custom synthesis of client-specific drug substances.

Basic Information

Product Name	Apimostinel
CAS No.	1421866-48-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Apimostinel; UNII-9K5J6QMF2T; 9K5J6QMF2T; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-guanidino-N-[(1S,2R)-1-[(carboxymethyl)carbamoyl]-2-hydroxypropyl]pentanamide; BMS-986177
EINECS	Contact for details

Quality Control

Our Apimostinel is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider conditions of 2-8°C. The material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.