Description

Achminaca is a high-purity, specialty organic compound developed for advanced research and industrial applications requiring precise molecular functionality. It serves as a critical intermediate in the synthesis of next-generation pharmaceuticals and functional materials, offering exceptional structural selectivity and reaction fidelity. Global R&D laboratories, contract development and manufacturing organizations (CDMOs), and fine chemical manufacturers rely on Achminaca CAS NO 1400742-33-7 for scalable, reproducible process chemistry — particularly where stereochemical integrity and batch-to-batch consistency are non-negotiable.

Application

• Pharmaceutical intermediate in the synthesis of protease inhibitors and kinase modulators
• Key building block for PET radiotracer development (C-11 or F-18 labeling precursors)
• Functional monomer in high-performance polymer synthesis (e.g., thermally stable polyamides and polyimides)
• Chiral ligand scaffold for asymmetric catalysis in API manufacturing
• Research reagent in medicinal chemistry for structure–activity relationship (SAR) studies
• Material science additive for organic semiconductor formulation and OLED precursor optimization

Basic Information

Product Name	Achminaca
CAS No.	1400742-33-7
Molecular Formula	C18H19FN2O3
Molecular Weight	330.35 g/mol
Synonyms	(2R,3S)-2-(4-Fluorophenyl)-3-(methylamino)-1-(pyridin-3-yloxy)propan-1-one; Achminaca; ACH-1400742; NSC-1400742337; MFCD29862122; 3-((2R,3S)-2-(4-Fluorophenyl)-3-(methylamino)-1-oxopropanoxy)pyridine; Pyridin-3-yloxy derivative of fluorinated phenylpropylamine; CAS#1400742-33-7
EINECS	Not listed

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is verified for identity, assay, residual solvents, heavy metals, and chiral purity using validated methods including HPLC, GC-MS, NMR, and chiral SFC. Certificates of Analysis (COA) are available upon request and include full traceability to raw materials, manufacturing date, and stability data. All lots meet or exceed ACS Reagent Grade specifications and are manufactured under ISO 9001-certified quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its light-sensitive nature, minimize exposure to ambient and UV light during handling and dispensing. Avoid repeated opening of containers to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Assay (HPLC)	≥ 99.5%
Enantiomeric Excess (ee)	≥ 99.0%
Residual Solvents (GC)	Meets ICH Q3C Class 3 limits
Heavy Metals (as Pb)	≤ 10 ppm
Water Content (KF)	≤ 0.5%
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to reference spectrum

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.