Description

(1R,2R)-2-Amino-1-Methylcyclopentan-1-Ol CAS NO 1400689-45-3 is a chiral amino alcohol derivative with a cyclopentane backbone, serving as a sophisticated building block in organic synthesis. This compound matters for its ability to impart stereochemical control in the creation of complex molecules, which is critical for developing pharmaceuticals with high efficacy and specificity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise molecular architecture is paramount.

Application

• As a key chiral intermediate in the synthesis of novel pharmaceutical compounds, particularly for central nervous system (CNS) and antiviral drug candidates.
• Utilized in the research and development of agrochemicals, such as herbicides and fungicides, requiring specific stereochemistry for optimal activity.
• Serves as a ligand or catalyst precursor in asymmetric synthesis to facilitate enantioselective chemical transformations.
• Employed in academic and industrial research for studying structure-activity relationships (SAR) in medicinal chemistry programs.
• Used in the preparation of specialty polymers and advanced materials where the amino alcohol functionality can modify material properties.
• Acts as a building block for the synthesis of complex natural products and their analogs in total synthesis projects.

Basic Information

Product Name	(1R,2R)-2-Amino-1-Methylcyclopentan-1-Ol
CAS No.	1400689-45-3
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(1R,2R)-1-Methyl-2-aminocyclopentanol; (1R,2R)-2-Amino-1-methylcyclopentanol; (1R,2R)-1-Methylcyclopentane-1,2-diamine (related diamine); trans-2-Amino-1-methylcyclopentan-1-ol; (1R,2R)-Amino-methylcyclopentanol; 1-Methyl-2-aminocyclopentanol (trans-); Cyclopentanemethanol, 2-amino-1-methyl-, (1R,2R)-; (1R,2R)-1-Methyl-2-aminocyclopentyl alcohol
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-Amino-1-Methylcyclopentan-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.