Description

2,4-Difluoro-5-Methoxyphenylboronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing difluoromethoxy-substituted aromatic systems.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic scaffolds for enhanced activity and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated molecules used as probes or tags in biochemical and medicinal research.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,4-Difluoro-5-Methoxyphenylboronic Acid
CAS No.	1395417-65-8
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(2,4-Difluoro-5-methoxyphenyl)boronic Acid; 5-Methoxy-2,4-difluorophenylboronic Acid; 2,4-Difluoro-5-methoxybenzeneboronic Acid; Boronic acid, B-(2,4-difluoro-5-methoxyphenyl)-; 1395417-65-8; 2,4-Difluoro-5-methoxy phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring material traceability and reliability in GMP or research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.