Description

3-(3-Fluorophenyl)Oxetane-3-Carboxylic Acid is a high-value, fluorinated oxetane derivative serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a strained oxetane ring and a fluorinated aromatic system, makes it an essential intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the metabolically stable oxetane moiety and fluorine atom to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorophenyl-oxetane unit can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, coatings, and liquid crystals with tailored thermal and optical properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes, leveraging its potential for bioorthogonal reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex molecules on a commercial scale.

Basic Information

Product Name	3-(3-Fluorophenyl)Oxetane-3-Carboxylic Acid
CAS No.	1393553-52-0
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	3-(3-Fluorophenyl)-3-oxetanecarboxylic acid; 3-Oxetanecarboxylic acid, 3-(3-fluorophenyl)-; 3-Fluoro-α,α-dimethylbenzenepropanoic acid, oxetane analog; 3-Carboxy-3-(3-fluorophenyl)oxetane; 3-(3-Fluorophenyl)oxetane-3-carboxylic acid; 3-(m-Fluorophenyl)oxetane-3-carboxylic acid; 1393553-52-0; Oxetane-3-carboxylic acid, 3-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Fluorophenyl)Oxetane-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (HPLC, NMR, GC) is supplied with each shipment to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.