Description

2,6-Dimethyl-4-Fluorophenylboronic Acid is a high-purity, synthetically valuable organoboron building block. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials scientists in the synthesis of novel active ingredients and functional compounds. Its specific substitution pattern offers unique steric and electronic properties for targeted molecular design.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring fluorinated aromatic structures.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.
• Fluorine Chemistry: The fluorine substituent makes it valuable for studying structure-activity relationships and improving metabolic stability in drug candidates.

Basic Information

Product Name	2,6-Dimethyl-4-Fluorophenylboronic Acid
CAS No.	1392512-54-7
Molecular Formula	C8H10BFO2
Molecular Weight	167.98 g/mol
Synonyms	(4-Fluoro-2,6-dimethylphenyl)boronic acid; 2,6-Dimethyl-4-fluorobenzeneboronic acid; 4-Fluoro-2,6-dimethylbenzeneboronic acid; B-(4-Fluoro-2,6-dimethylphenyl)boronic acid; 2,6-Dimethyl-4-fluorophenyl-B(OH)2; 2,6-Dimethyl-4-fluorophenylboronic acid pinacol ester (common derivative); 4-Fluoro-2,6-xylylboronic acid
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.