Description

Carbovir Triphosphate Triethylamine Salt is a chemically modified nucleotide analog triphosphate, a critical reagent for biochemical and pharmaceutical research. Its primary value lies in serving as a high-purity, stabilized substrate for enzymatic studies, particularly in virology and antiviral drug development. This compound is essential for researchers and manufacturers in the fields of nucleic acid synthesis, molecular biology, and antiviral pharmaceutical development, where precise and reliable nucleotide analogs are required.

Application

• Biochemical Research: As a substrate for DNA/RNA polymerases and reverse transcriptase enzymes in kinetic and mechanistic studies.
• Antiviral Drug Development: Critical for in vitro evaluation of carbovir (a guanosine analog) incorporation and its inhibitory effects on viral replication.
• Nucleotide Metabolism Studies: Used to investigate cellular uptake and phosphorylation pathways of nucleoside analogs.
• Enzyme Assay Development: Serves as a key component in high-throughput screening assays for discovering novel polymerase inhibitors.
• Reference Standard: Acts as a certified reference material (CRM) for quality control in pharmaceutical manufacturing of related antiviral agents.
• Proteomics & Genomics: Utilized in specialized techniques requiring modified nucleotide triphosphates for labeling or chain termination.

Basic Information

Product Name	Carbovir Triphosphate Triethylamine Salt
CAS No.	1391048-07-9
Molecular Formula	C₁₈H₃₃N₆O₁₃P₃ • C₆H₁₅N
Molecular Weight	Contact for details
Synonyms	Carbovir-TP TEA Salt; (-)-Carbovir Triphosphate Triethylammonium Salt; 9-[(1R,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]guanine Triphosphate TEA Salt; 9-[(1R,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]-9H-guanine 5'-(trihydrogen triphosphate) triethylamine salt; NSC 614846 TEA Salt; Abacavir precursor triphosphate salt; Cyclopentenyl-Guanine Triphosphate TEA Salt
EINECS	Contact for details

Quality Control

Our Carbovir Triphosphate Triethylamine Salt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Triethylamine Content	1.0 - 3.0 eq
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.