Description

Methyl 2-Fluoro-3-(4-Fluoro-3-Methoxyphenyl)Benzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine substitution pattern is critical for modulating biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate sophisticated fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed to introduce fluorine-containing side chains or monomers, modifying polymer properties like solvent resistance and thermal stability.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination reactions or cross-coupling methodologies in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	Methyl 2-Fluoro-3-(4-Fluoro-3-Methoxyphenyl)Benzoate
CAS No.	1381944-46-2
Molecular Formula	C15H12F2O3
Molecular Weight	278.25 g/mol
Synonyms	2-Fluoro-3-(4-fluoro-3-methoxyphenyl)benzoic acid methyl ester; Methyl 2-fluoro-3-(4-fluoro-3-methoxyphenyl)benzoate; Benzoic acid, 2-fluoro-3-(4-fluoro-3-methoxyphenyl)-, methyl ester; 3-(4-Fluoro-3-methoxyphenyl)-2-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-3-(4-Fluoro-3-Methoxyphenyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.