Description

Methyl 3-[4-(Dimethylcarbamoyl)Phenyl]-2-Fluorobenzoate is a high-purity fluorinated benzoate derivative, serving as a critical advanced intermediate in modern organic synthesis. Its molecular structure, featuring both a fluorobenzoate ester and a dimethylcarbamoylphenyl group, makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the synthesis of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used in academic and industrial research to develop novel ligands for catalytic systems or as a scaffold in material science.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines for clinical trial materials.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	Methyl 3-[4-(Dimethylcarbamoyl)Phenyl]-2-Fluorobenzoate
CAS No.	1381944-34-8
Molecular Formula	C17H16FNO3
Molecular Weight	301.31 g/mol
Synonyms	Methyl 2-Fluoro-3-[4-(dimethylcarbamoyl)phenyl]benzoate; 3-[4-(Dimethylcarbamoyl)Phenyl]-2-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 3-[4-(dimethylaminocarbonyl)phenyl]-2-fluoro-, methyl ester; 2-Fluoro-3-(4-(dimethylcarbamoyl)phenyl)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-[4-(Dimethylcarbamoyl)Phenyl]-2-Fluorobenzoate adheres to stringent internal quality standards, ensuring batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement a quality management system aligned with ISO principles, and material can be supplied under a Quality Agreement to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.