Description

5-(((tert-Butoxycarbonyl)Amino)Methyl)-2-(Trifluoromethyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. Its core value lies in its role as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. This compound is essential for research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those containing trifluoromethyl and protected amine functionalities.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors, a major class of therapeutics for viral infections and other diseases.
• PET Tracer Synthesis: Serves as a starting material or intermediate in the creation of Positron Emission Tomography (PET) radiotracers for diagnostic imaging.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes to study enzyme function and protein-protein interactions.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents leveraging the stability of the trifluoromethyl group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects under cGMP guidelines.

Basic Information

Product Name	5-(((tert-Butoxycarbonyl)Amino)Methyl)-2-(Trifluoromethyl)Benzoic Acid
CAS No.	1381846-32-7
Molecular Formula	C15H18F3NO4
Molecular Weight	333.30 g/mol
Synonyms	5-((Boc-Amino)Methyl)-2-(Trifluoromethyl)Benzoic Acid; 2-(Trifluoromethyl)-5-(((tert-butoxycarbonyl)amino)methyl)benzoic acid; 5-(((tert-Butoxycarbonyl)amino)methyl)-2-(trifluoromethyl)benzoic acid; Boc-AMB-2-TFBA; N-Boc-5-(aminomethyl)-2-(trifluoromethyl)benzoic acid; tert-Butyl [5-(carboxy)-2-(trifluoromethyl)benzyl]carbamate; BOC-AMBA-TFM
EINECS	Contact for details

Quality Control

Our 5-(((tert-Butoxycarbonyl)Amino)Methyl)-2-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.