Description

Methyl 2,6-Difluoro-3-Methoxybenzoate is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its precise molecular architecture, which enables the efficient construction of complex molecules for demanding applications. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoro-methoxy benzoate moiety can impart superior activity and selectivity.
• Liquid Crystal & Electronic Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic electronic materials, contributing to improved performance in displays and semiconductors.
• Organic Synthesis Research: A versatile reagent for coupling reactions (e.g., Suzuki, Stille) and further functionalization, enabling medicinal and process chemists to explore new chemical space.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 2,6-Difluoro-3-Methoxybenzoate
CAS No.	1379300-37-4
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2,6-Difluoro-3-methoxybenzoic acid methyl ester; Methyl 2,6-difluoro-3-methoxybenzoate; Benzoic acid, 2,6-difluoro-3-methoxy-, methyl ester; 3-Methoxy-2,6-difluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,6-Difluoro-3-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.