Description

2,3-Difluoro-6-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the precise introduction of fluorine and methyl substituents, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as by specialty chemical producers for creating advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro-methyl benzoate structure contributes to enhanced biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, improving charge transport, thermal stability, and optical properties in display technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing chemical resistance, lowering surface energy, and improving material durability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and carboxylate derivatization for constructing complex, fluorinated molecular architectures in medicinal and material chemistry.

Basic Information

Product Name	2,3-Difluoro-6-Methylbenzoic Acid
CAS No.	1378671-01-2
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2,3-Difluoro-6-methylbenzoic acid; 6-Methyl-2,3-difluorobenzoic acid; 2,3-Difluoro-6-toluic acid; Benzoic acid, 2,3-difluoro-6-methyl-; 2,3-Difluoro-6-methyl-benzoic acid; 1378671-01-2 (CAS); 2,3-Difluoro-6-methylbenzoate
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Methylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with complete batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.