Description

Methyl 2-(Chlorosulfonyl)-5-Fluorobenzoate is a high-purity, multi-functional chemical intermediate characterized by its reactive chlorosulfonyl and ester functional groups. This compound is essential for the synthesis of complex molecules, offering a versatile building block for advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide or benzoate motifs for therapeutic applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and advanced functional materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeling reagents for biochemical and diagnostic research due to its reactive sites.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 2-(Chlorosulfonyl)-5-Fluorobenzoate
CAS No.	1374249-78-1
Molecular Formula	C8H6ClFO4S
Molecular Weight	252.65 g/mol
Synonyms	5-Fluoro-2-(chlorosulfonyl)benzoic acid methyl ester; Methyl 5-fluoro-2-(chlorosulfonyl)benzoate; 2-(Chlorosulfonyl)-5-fluorobenzoic acid methyl ester; Benzoic acid, 2-(chlorosulfonyl)-5-fluoro-, methyl ester; Methyl 2-chlorosulfonyl-5-fluorobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(Chlorosulfonyl)-5-Fluorobenzoate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.