Description

Benzoic Acid, 4,5-Difluoro-2-Formyl- is a high-value, multi-functional aromatic building block characterized by its difluoro and formyl substituents. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, offering precise reactivity for constructing advanced chemical architectures. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the difluoro motif enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful in constructing fluorescent tags or molecular probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Benzoic Acid, 4,5-Difluoro-2-Formyl-
CAS No.	1374150-50-1
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	4,5-Difluoro-2-formylbenzoic acid; 2-Formyl-4,5-difluorobenzoic acid; 4,5-Difluoro-2-carboxybenzaldehyde; 2-Carboxy-4,5-difluorobenzaldehyde; 4,5-Difluorophthalaldehydic acid; Benzoic acid, 4,5-difluoro-2-formyl- (CAS 1374150-50-1)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4,5-Difluoro-2-Formyl- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment supports cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen) to prevent oxidation and moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.