Description

Methyl 5-(3-Aminophenyl)-2-Fluorobenzoate, Hcl is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic and fluorinated structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables targeted molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides and fungicides with enhanced efficacy.
• Material Science: Used in the research and development of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: An important reagent for introducing fluorinated aromatic motifs into complex organic molecules in medicinal chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and scale-up process development.

Basic Information

Product Name	Methyl 5-(3-Aminophenyl)-2-Fluorobenzoate, Hcl
CAS No.	1373232-80-4
Molecular Formula	C14H13FNO2 • HCl
Molecular Weight	281.72 (Free base) / 318.18 (HCl salt)
Synonyms	Methyl 5-(3-Aminophenyl)-2-fluorobenzoate hydrochloride; 2-Fluoro-5-(3-aminophenyl)benzoic acid methyl ester hydrochloride; Benzoic acid, 5-(3-aminophenyl)-2-fluoro-, methyl ester, hydrochloride; Methyl 2-fluoro-5-(m-aminophenyl)benzoate HCl
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(3-Aminophenyl)-2-Fluorobenzoate, Hcl adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.