Description

2-Amino-9-((1R,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methylenecyclopentyl)-1,9-Dihydro-6H-Purin-6-One Hydrate is a high-purity nucleoside analogue of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate and building block for the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Research: Used in the research and development of therapeutics targeting specific viral polymerases and replication mechanisms.
• Oncology Research: Serves as a precursor in the development of chemotherapeutic agents designed to interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand cellular processes and nucleotide metabolism.
• Process Chemistry: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under GMP or non-GMP conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-Amino-9-((1R,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methylenecyclopentyl)-1,9-Dihydro-6H-Purin-6-One Hydrate
CAS No.	1367369-78-5
Molecular Formula	C12H15N5O3 · xH2O
Molecular Weight	277.28 (Anhydrous basis)
Synonyms	9-[(1R,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]purin-6-amine hydrate; 2-Amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one hydrate; 2-Amino-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one monohydrate; Nucleoside analogue intermediate; Cyclopentyl purine derivative.
EINECS	Contact for details

Quality Control

Our 2-Amino-9-((1R,3R,4S)-4-Hydroxy-3-(Hydroxymethyl)-2-Methylenecyclopentyl)-1,9-Dihydro-6H-Purin-6-One Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.