Description

(1S,2R,3S,4R)-3-Carbamoylbicyclo[2.2.1]Heptane-2-Carboxylic Acid is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its rigid, functionalized norbornane-like structure makes it a valuable scaffold for developing novel pharmaceuticals and fine chemicals with precise three-dimensional architectures. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalysis Ligand Synthesis: Used to construct sophisticated, rigid ligands for transition metal catalysts that control stereoselectivity.
• Peptidomimetics & Conformationally Restricted Analogs: Serves as a core structure to mimic peptide turn motifs and create bioactive compounds with enhanced metabolic stability.
• Material Science Research: Building block for novel polymers and organic frameworks where its rigid, polycyclic geometry imparts specific physical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Academic & Process Chemistry: Enables methodological studies in synthetic organic chemistry and the development of scalable routes to complex molecules.

Basic Information

Product Name	(1S,2R,3S,4R)-3-Carbamoylbicyclo[2.2.1]Heptane-2-Carboxylic Acid
CAS No.	1365987-23-0
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	(1S,2R,3S,4R)-3-Carbamoylbicyclo[2.2.1]heptane-2-carboxylic acid; endo-3-Carbamoylbicyclo[2.2.1]heptane-2-carboxylic acid (stereoisomer); Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-carbamoyl-, (1S,2R,3S,4R)-; 3-Carbamoylnorbornane-2-carboxylic acid; (1S,2R,3S,4R)-3-Aminocarbonylbicyclo[2.2.1]heptane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of (1S,2R,3S,4R)-3-Carbamoylbicyclo[2.2.1]Heptane-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to meet the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or with appropriate desiccant to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.