Description

2-Amino-5-Fluoro-4-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and methoxy substituents, makes it an invaluable intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new herbicides and pesticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Synthesis: Intermediate for producing advanced fluorinated dyes and functional pigments with specific light-absorption properties.
• Material Science: Building block for synthesizing monomers used in specialty polymers and high-performance materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	2-Amino-5-Fluoro-4-Methoxybenzoic Acid
CAS No.	1363380-91-9
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	5-Fluoro-2-amino-4-methoxybenzoic acid; 4-Methoxy-2-amino-5-fluorobenzoic acid; 2-Amino-4-methoxy-5-fluorobenzoic acid; Benzoic acid, 2-amino-5-fluoro-4-methoxy-; 1363380-91-9; 5-Fluoro-4-methoxyanthranilic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoro-4-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.