Description

3-(Methoxycarbonyl)-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its dual functionality, serving as a key building block in cross-coupling reactions to construct complex molecular architectures. This compound is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging the trifluoromethyl group to enhance metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a building block for constructing sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and emissive materials for OLEDs, due to its electron-withdrawing substituents.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for studying biological processes and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(Methoxycarbonyl)-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1360771-83-0
Molecular Formula	C9H8BF3O4
Molecular Weight	247.97 g/mol
Synonyms	(3-(Methoxycarbonyl)-5-(trifluoromethyl)phenyl)boronic acid; 3-Carbomethoxy-5-(trifluoromethyl)benzeneboronic acid; Methyl 3-borono-5-(trifluoromethyl)benzoate; 5-(Trifluoromethyl)-3-methoxycarbonylphenylboronic acid; Benzoic acid, 3-borono-5-(trifluoromethyl)-, methyl ester; Boronic acid, B-[3-(methoxycarbonyl)-5-(trifluoromethyl)phenyl]-; CAS 1360771-83-0
EINECS	Contact for details

Quality Control

Our 3-(Methoxycarbonyl)-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.