Description

3-Bromo-4-Chloro-5-Fluorobenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those targeting specific receptors where halogen atoms modulate bioactivity and metabolic stability.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, where the halogen pattern can influence binding to biological targets.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its ability to influence molecular packing and electronic properties.
• Chemical Biology Probes: Serves as a scaffold for creating labeled compounds and molecular probes used in diagnostic and mechanistic studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects.

Basic Information

Product Name	3-Bromo-4-Chloro-5-Fluorobenzoic Acid
CAS No.	1357942-87-0
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	Benzoic acid, 3-bromo-4-chloro-5-fluoro-; 3-Bromo-4-chloro-5-fluorobenzoic acid; 5-Fluoro-3-bromo-4-chlorobenzoic acid; 4-Chloro-3-bromo-5-fluorobenzoic acid; 3-Br-4-Cl-5-F-BA; BCFBA
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Chloro-5-Fluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.