Description

1-{(2S)-1-[(11Br)-2,6-Bis(Trimethylsilyl)Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]Propan-2-Yl}-3-Phenylurea is a high-purity, chiral organophosphorus compound with a minimum assay of 97%. This advanced intermediate is valued for its role in asymmetric synthesis, particularly as a ligand or catalyst precursor in transition metal catalysis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Asymmetric Catalysis: Serves as a sophisticated chiral ligand or precursor for catalysts in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Research & Development: A critical building block for synthesizing chiral drug candidates and complex molecular scaffolds in medicinal chemistry.
• Process Chemistry: Used in the development and scale-up of stereoselective synthetic routes for fine chemicals and APIs.
• Academic Research: Employed in methodological studies to explore new catalytic systems and reaction mechanisms in organic synthesis.
• Material Science: Potential applications in the synthesis of chiral polymers or advanced functional materials with specific optical properties.

Basic Information

Product Name	1-{(2S)-1-[(11Br)-2,6-Bis(Trimethylsilyl)Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yloxy]Propan-2-Yl}-3-Phenylurea
CAS No.	1357562-70-9
Molecular Formula	C41H49BrNO4PSi2
Molecular Weight	811.88 g/mol
Synonyms	(S)-1-(1-((11bR)-2,6-Bis(trimethylsilyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yloxy)propan-2-yl)-3-phenylurea; BINAP-Derived Chiral Urea Phosphite; Chiral Dinaphthodioxaphosphepin Urea Ligand; (11bR)-4-(((S)-1-(3-Phenylureido)propan-2-yl)oxy)-2,6-bis(trimethylsilyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under strict quality control protocols to ensure identity, purity, and chiral integrity. Our standard 97% minimum purity is verified by advanced analytical techniques including HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profile is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Chiral Purity (Chiral HPLC)	Min. 99.0% ee
Loss on Drying	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.