Description

2-(2-Carboxyphenyl)-5-Fluorobenzoic Acid is a high-purity, bifunctional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its dual carboxylic acid groups and fluorine substituent, which provide versatile reactivity for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in metal-organic frameworks (MOFs) and homogeneous catalysis.
• Polymer Chemistry: A monomer for creating specialty polyesters and polyamides with unique thermal and chemical resistance properties.
• Material Science Research: Employed in the synthesis of organic semiconductors and liquid crystal materials for electronic applications.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services targeting complex, fluorinated target molecules.

Basic Information

Product Name	2-(2-Carboxyphenyl)-5-Fluorobenzoic Acid
CAS No.	1355247-36-7
Molecular Formula	C14H9FO4
Molecular Weight	260.22 g/mol
Synonyms	5-Fluoro-2,2'-dicarboxybiphenyl; 2'-Carboxy-5-fluorobiphenyl-2-carboxylic Acid; [1,1'-Biphenyl]-2,2'-dicarboxylic acid, 5'-fluoro-; 5'-Fluoro[1,1'-biphenyl]-2,2'-dicarboxylic Acid; 2-(2-Carboxyphenyl)-5-fluorobenzoic Acid; 5-Fluoro-2,2'-biphenyldicarboxylic Acid; 2,2'-Biphenyldicarboxylic Acid, 5-Fluoro Derivative
EINECS	Contact for details

Quality Control

Our 2-(2-Carboxyphenyl)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.