Description

(S,S)-(-)-1,2-Bis(T-Butylmethylphosphino)Benzene (S,S)-Benzp* CAS NO 1355162-85-4 is a high-value, chiral bisphosphine ligand essential for creating highly selective asymmetric catalysts. Its primary value lies in enabling efficient and enantioselective transformations critical for synthesizing complex, single-enantiomer molecules. This product is indispensable for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in hydrogenation, cross-coupling, and other catalytic reactions.

Application

• As a key ligand in asymmetric hydrogenation catalysts for the production of chiral pharmaceutical intermediates and active ingredients.
• Enabling enantioselective cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) in fine chemical synthesis.
• Use in hydroformylation and hydroamination catalysis to create chiral aldehydes and amines.
• Critical component in academic and industrial R&D for developing novel catalytic methodologies.
• Catalyst systems for the synthesis of natural products and complex organic molecules with defined stereocenters.
• Potential applications in material science for creating chiral polymers or surfaces.

Basic Information

Product Name	(S,S)-(-)-1,2-Bis(T-Butylmethylphosphino)Benzene (S,S)-Benzp*
CAS No.	1355162-85-4
Molecular Formula	C20H36P2
Molecular Weight	338.44 g/mol
Synonyms	(S,S)-Benzp*; (S,S)-(-)-1,2-Bis(tert-Butylmethylphosphino)benzene; (S,S)-1,2-Bis[(tert-butyl)methylphosphino]benzene; (S,S)-DTBMB; (S,S)-1,2-Bis(tert-butylmethylphosphanyl)benzene; (S,S)-BenzP* ligand; (1S,2S)-1,2-Bis[(tert-butyl)methylphosphino]benzene
EINECS	Contact for details

Quality Control

Our (S,S)-Benzp* is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric excess. Each lot undergoes comprehensive analytical characterization, including chiral HPLC, NMR, and elemental analysis. A Certificate of Analysis (COA) detailing purity, chiral purity, and identity is provided with every shipment, supporting compliance with cGMP and other stringent regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation [α]D20	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.