Description

4-Fluoro-2-(Hydroxymethyl)Benzoic Acid is a versatile fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a hydroxymethyl group on a fluorinated aromatic ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, anti-inflammatory, and oncology applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, enhancing material properties like chemical resistance, thermal stability, and weatherability.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination chemistry and synthesizing complex organic molecules.
• Diagnostic Agent Precursor: Potential intermediate in the development of fluorinated contrast agents or probes used in medical imaging techniques such as PET (Positron Emission Tomography).

Basic Information

Product Name	4-Fluoro-2-(Hydroxymethyl)Benzoic Acid
CAS No.	1354960-91-0
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	2-(Hydroxymethyl)-4-fluorobenzoic Acid; 4-Fluoro-2-(hydroxymethyl)benzoic acid; Benzoic acid, 4-fluoro-2-(hydroxymethyl)-; 4-Fluoro-2-hydroxymethylbenzoic Acid; 2-Carboxy-5-fluorobenzyl Alcohol; 5-Fluoro-2-(hydroxymethyl)benzoic Acid (alternative numbering); 4-Fluoro-2-(hydroxymethyl)-benzoic Acid; 4-F-2-HMBA
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-2-(Hydroxymethyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assay and identity confirmation via FT-IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.