Description

3,5-Difluoro-4-(Oxetan-3-Yloxy)Benzoic Acid is a high-value, multifunctional benzoic acid derivative featuring a unique oxetane ether linkage and fluorine substitution. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in modern organic synthesis, enabling the development of complex molecules with tailored properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drugs, particularly in kinase inhibitor and other targeted therapy research programs.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorine atoms and oxetane moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom synthesis projects requiring this specific fluorinated aromatic scaffold.

Basic Information

Item	Details
Product Name	3,5-Difluoro-4-(Oxetan-3-Yloxy)Benzoic Acid
CAS No.	1349717-87-8
Molecular Formula	C10H8F2O4
Molecular Weight	230.17 g/mol
Synonyms	4-(Oxetan-3-yloxy)-3,5-difluorobenzoic Acid; 3,5-Difluoro-4-(3-oxetanyloxy)benzoic Acid; Benzoic acid, 3,5-difluoro-4-(oxetan-3-yloxy)-; 1349717-87-8; 3,5-Difluoro-4-(oxetane-3-yloxy)benzoic acid; 3,5-Difluoro-4-(oxetan-3-yloxy)-benzoic acid; 3,5-Difluoro-4-(3-oxetanyloxy)-benzoic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(Oxetan-3-Yloxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support compliance with ICH guidelines for impurities and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong alkali and should be kept separate from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.