Description

2-Amino-4,6-Dichloropyrimidine-13C2 is a stable isotope-labeled analog of a key pyrimidine building block, where two carbon atoms are replaced with the 13C isotope. This compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and developers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic pathway studies, and the synthesis of labeled complex molecules.

Application

• Internal Standard for LC/MS and GC/MS: Provides highly accurate quantification in bioanalytical and pharmacokinetic studies due to its isotopic purity.
• Metabolic Research & Tracing: Used to investigate drug metabolism, degradation pathways, and environmental fate studies of related agrochemicals.
• Synthesis of Isotope-Labeled APIs: Serves as a critical labeled precursor in the development of stable isotope-labeled active pharmaceutical ingredients (APIs) for clinical trials.
• Nucleic Acid & Heterocyclic Chemistry Research: A fundamental building block for creating labeled pyrimidine derivatives in academic and industrial R&D.
• Quality Control & Method Development: Employed in analytical laboratories to develop and validate sensitive and specific assay methods.

Basic Information

Product Name	2-Amino-4,6-Dichloropyrimidine-13C2
CAS No.	1346605-11-5
Molecular Formula	C213C2H3Cl2N3
Molecular Weight	167.98 (for 13C2 labeled form)
Synonyms	4,6-Dichloro-2-pyrimidinamine-13C2; 2-Pyrimidinamine, 4,6-dichloro-13C2; 4,6-Dichloro-2-aminopyrimidine-13C2; 13C2-Labeled 2-Amino-4,6-dichloropyrimidine; ACDP-13C2; Isotopically Labeled Pyrimidine Building Block
EINECS	Contact for details

Quality Control

Our 2-Amino-4,6-Dichloropyrimidine-13C2 is produced under strict quality management systems. Each batch is characterized and tested to ensure high isotopic enrichment and chemical purity, critical for sensitive analytical applications. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as isotopic purity (e.g., 13C atom %), chemical purity by HPLC, and identification by NMR and MS. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C atom %)	≥ 99%
Isotopic Enrichment (MS)	≥ 98% (13C2)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.