Description

2-Fluoro-5-(1-Methyl-1H-Pyrazol-5-Yl)Benzoic Acid is a high-value fluorinated aromatic building block that combines a benzoic acid core with a substituted pyrazole moiety. This unique structure makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds and agrochemicals, particularly those targeting specific biological pathways. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients. The compound's defined structure, with CAS NO 1342382-45-9, ensures precise molecular architecture for downstream applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Advanced Material Development: Incorporated into specialty polymers and organic electronic materials to modify their properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Fluoro-5-(1-Methyl-1H-Pyrazol-5-Yl)Benzoic Acid
CAS No.	1342382-45-9
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	2-Fluoro-5-(1-methyl-1H-pyrazol-5-yl)benzoic acid; 5-(2-Fluorophenyl)-1-methyl-1H-pyrazole-3-carboxylic acid (tautomer); 1342382-45-9; Benzoic acid, 2-fluoro-5-(1-methyl-1H-pyrazol-5-yl)-; 2-Fluoro-5-(1-methylpyrazol-5-yl)benzoic acid; 5-(2-Fluorobenzoyl)-1-methyl-1H-pyrazole; 1-Methyl-5-(2-fluorobenzoyl)pyrazole
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-5-(1-Methyl-1H-Pyrazol-5-Yl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. Certificates of Analysis (COA) detailing all test results are provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0% Any single impurity ≤1.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.