Description

(S)-2-[Diphenyl[[Trisisopropylsilyl]Oxy]Methyl]Pyrrolidine is a high-purity, chiral organosilicon compound used as a key building block and chiral auxiliary in advanced organic synthesis. Its value lies in its ability to induce stereoselectivity in complex reactions, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for asymmetric synthesis.

Application

• As a chiral auxiliary in the asymmetric synthesis of active pharmaceutical ingredients (APIs).
• As a key intermediate in the preparation of complex natural products and bioactive molecules.
• For use in stereoselective carbon-carbon bond-forming reactions, such as aldol additions.
• In catalyst and ligand development for enantioselective catalysis.
• In process chemistry for the scale-up of chiral drug candidates.
• As a reference standard for analytical method development and quality control in chiral separations.

Basic Information

Product Name	(S)-2-[Diphenyl[[Trisisopropylsilyl]Oxy]Methyl]Pyrrolidine
CAS No.	1339961-44-2
Molecular Formula	C27H41NO2Si
Molecular Weight	439.71 g/mol
Synonyms	(S)-2-(Diphenyl((tris(isopropyl)silyl)oxy)methyl)pyrrolidine; (S)-TIPS-DPMP; (S)-2-[(Diphenylhydroxymethyl)]pyrrolidine tris(isopropyl)silyl ether; (S)-N-TIPS-DPMP; (S)-TIPS-protected diphenylprolinol; (S)-α,α-Diphenyl-2-pyrrolidinemethanol tris(isopropyl)silyl ether; (S)-O-TIPS-Diphenylprolinol
EINECS	Contact for details

Quality Control

Our (S)-2-[Diphenyl[[Trisisopropylsilyl]Oxy]Methyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee product identity, purity, and consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.