Description

Benzoic Acid, 5-Bromo-3-Fluoro-2-Iodo- is a highly functionalized benzoic acid derivative, distinguished by its unique halogen substitution pattern which makes it a valuable and versatile building block in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecules for research and development, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for medicinal chemists and process development scientists seeking to introduce specific halogen atoms for bioactivity modulation or as synthetic handles for further derivatization.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, where the halogen atoms can enhance binding affinity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of functionalized polymers and liquid crystals, where halogenated aromatic units influence material properties.
• Chemical Biology: Acts as a probe or linker molecule in bioconjugation and the development of molecular imaging agents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, multi-halogenated aromatic frameworks.

Basic Information

Product Name	Benzoic Acid, 5-Bromo-3-Fluoro-2-Iodo-
CAS No.	1335511-41-5
Molecular Formula	C7H3BrFIO2
Molecular Weight	344.90 g/mol
Synonyms	5-Bromo-3-fluoro-2-iodobenzoic acid; 2-Iodo-5-bromo-3-fluorobenzoic acid; Benzoic acid, 5-bromo-3-fluoro-2-iodo-; 1335511-41-5; 3-Fluoro-5-bromo-2-iodobenzoic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 5-Bromo-3-Fluoro-2-Iodo- is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity (typically by HPLC), and levels of specific impurities. Our quality systems are designed to support customer needs for regulatory filings and GMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.