Description

5-Chlorodescyano Citalopram Hydrobromide is a key pharmaceutical intermediate and reference standard used in advanced research and development. This compound is critical for the synthesis and analytical characterization of novel active pharmaceutical ingredients (APIs) and their metabolites. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers specializing in neuropharmacology and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel citalopram analogs and related central nervous system (CNS) active compounds.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing to ensure product purity and consistency.
• Metabolite Research: Serves as a standard for the identification and quantification of drug metabolites in pharmacokinetic and bioanalytical studies.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex organic molecules.
• Academic Research: Used in university and institutional labs for studying structure-activity relationships (SAR) and serotonin reuptake inhibition mechanisms.

Basic Information

Product Name	5-Chlorodescyano Citalopram Hydrobromide
CAS No.	1332724-08-9
Molecular Formula	C20H22BrClFN2O
Molecular Weight	449.76 g/mol
Synonyms	1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-5-chloro-1,3-dihydroisobenzofuran-1-carbonitrile Hydrobromide; 5-Chloro-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-carbonitrile Hydrobromide; 5-Chloro Descyano Citalopram HBr; Citalopram Impurity; Citalopram Related Compound
EINECS	Contact for details

Quality Control

Our 5-Chlorodescyano Citalopram Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.