Description

6-Amino-5-Nitro-2-Thio-Uracil-13C2,15N is a stable isotope-labeled derivative of a key uracil heterocycle, essential for advanced analytical and research applications. This compound matters because it provides the isotopic purity and structural integrity required for precise quantification in mass spectrometry and metabolic pathway studies. Pharmaceutical researchers, agrochemical developers, and academic institutions engaged in tracer studies and method development are the primary users who need this high-value material.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in bioanalytical method development for drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolic Pathway Tracer: Used in isotopic labeling experiments to investigate the biosynthesis and degradation pathways of nucleobase analogs.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities or degradation products in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in environmental fate studies to track the metabolism and breakdown of related pesticidal compounds.
• Chemical Synthesis Intermediate: Acts as a building block for the synthesis of more complex, isotopically labeled heterocyclic compounds for research purposes.

Basic Information

Product Name	6-Amino-5-Nitro-2-Thio-Uracil-13C2,15N
CAS No.	1330266-31-3
Molecular Formula	C213C2H4N215N2O3S
Molecular Weight	Contact for details
Synonyms	6-Amino-5-nitro-2-thiouracil-13C2,15N; 2-Thio-6-amino-5-nitrouracil-13C2,15N; 5-Nitro-2-thio-6-aminouracil-13C2,15N; ANTU-13C2,15N; 6-Amino-5-nitro-2-mercapto-4-pyrimidinol-13C2,15N; Isotopically labeled 6-amino-5-nitro-2-thiouracil; Stable isotope labeled uracil derivative
EINECS	Contact for details

Quality Control

Every batch of 6-Amino-5-Nitro-2-Thio-Uracil-13C2,15N is produced and tested under strict quality management systems to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Isotopic Enrichment (15N)	≥ 99 atom %
Chemical Purity (NMR)	≥ 97.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.