Description

o-Pentylresorufin-D11 is a deuterated isotopologue of o-pentylresorufin, a specialized chemical compound used as a critical substrate and internal standard. This high-purity, labeled compound is essential for advanced analytical and research applications where precision and traceability are paramount. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and diagnostic manufacturers engaged in enzyme activity studies, particularly for cytochrome P450 isoforms, and in the development of sensitive bioanalytical assays.

Application

• Primary substrate for cytochrome P450 2A6 (CYP2A6) enzyme activity assays in drug metabolism studies.
• Use as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for accurate quantification of its non-deuterated counterpart.
• Critical reagent in high-throughput screening (HTS) platforms for evaluating drug-drug interactions and enzyme inhibition.
• Tool compound in biochemical research focusing on dealkylation reactions and metabolic pathway elucidation.
• Component in diagnostic kit development for pharmacogenetic testing related to CYP2A6 phenotype.
• Reference material for method development and validation in regulatory-compliant bioanalysis.

Basic Information

Product Name	o-Pentylresorufin-D11
CAS No.	1329614-81-4
Molecular Formula	C₁₈H₇D₁₁NO₃
Molecular Weight	~313.4 g/mol
Synonyms	7-Pentylresorufin-d11; 7-Pentoxyresorufin-d11; Pentoxyresorufin-d11; O-Pentylresorufin-d11; CYP2A6 Substrate-d11; 3H-Phenoxazin-3-one, 7-(pentyloxy)-2-(pentyl-d11)-; 7-(Pentyloxy)-2-(1,1,2,2,3,3,4,4,5,5,5-undecadeuteriopentyl)-3H-phenoxazin-3-one
EINECS	Contact for details

Quality Control

Every batch of o-Pentylresorufin-D11 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet exacting standards. Our quality assurance protocols are designed to support regulatory submissions. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), isotopic purity (by MS), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant use and storage under inert atmosphere.

Specification

Item	Specification
Appearance	Red to orange solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.