Description

Xanthurenic Acid-D4 is a stable isotope-labeled analog of the endogenous tryptophan metabolite, xanthurenic acid. This high-purity deuterated standard is essential for achieving precise and reliable quantification in advanced analytical workflows. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, clinical diagnostics, and metabolomics fields for applications requiring the highest level of accuracy, such as internal standardization in mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of xanthurenic acid in complex biological matrices like plasma, serum, and urine.
• Metabolomics Research: Used in tracer studies to investigate the kynurenine pathway and its role in neurological disorders, immune function, and metabolic diseases.
• Biomarker Analysis: Enables precise measurement of xanthurenic acid levels as a potential biomarker for conditions such as vitamin B6 deficiency, diabetes, and certain cancers.
• Drug Metabolism & Pharmacokinetics (DMPK): Supports studies on drug-induced alterations in tryptophan metabolism.
• Method Development & Validation: Serves as a key reference material for developing and validating robust bioanalytical assays in compliance with GLP guidelines.
• Quality Control in Diagnostic Kits: Used in the manufacturing and calibration of in-vitro diagnostic (IVD) kits targeting tryptophan metabolites.

Basic Information

Product Name	Xanthurenic Acid-D4
CAS No.	1329611-28-0
Molecular Formula	C10H3D4NO4
Molecular Weight	209.18 g/mol
Synonyms	4,8-Dihydroxyquinaldic Acid-d4; 4,8-Dihydroxy-2-quinolinecarboxylic Acid-d4; 8-Hydroxykynurenic Acid-d4; Xanthurenic Acid (tetradeutero); XA-d4; [D4]-Xanthurenic Acid; 2-Quinolinecarboxylic acid, 4,8-dihydroxy-, (tetradeutero)-; Stable Isotope Labeled Xanthurenic Acid
EINECS	Contact for details

Quality Control

Our Xanthurenic Acid-D4 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity (≥95% by HPLC), and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.