Description

4,6-Dimethyl-2(1H)-Pyrimidinone-13C,15N2 Hydrochloride is a stable isotope-labeled derivative of a key pyrimidinone scaffold, essential for advanced analytical and research applications. This compound provides a critical internal standard for precise quantification in mass spectrometry, ensuring data accuracy and reliability in complex matrices. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and agrochemical developers engaged in metabolism studies, pharmacokinetic profiling, and environmental fate analysis.

Application

• Internal Standard for LC-MS/MS: Serves as a critical reference compound for the accurate quantification of pyrimidinone analogs and their metabolites in biological and environmental samples.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in tracer studies to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of new chemical entities.
• Proteomics and Metabolomics Research: Enables precise tracking and identification in high-throughput screening and biomarker discovery workflows.
• Agrochemical Research: Applied in studies to determine the environmental fate, degradation pathways, and residue levels of related active ingredients.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex isotopically labeled molecules for research purposes.
• Quality Control and Method Development: Employed in analytical laboratories to validate and calibrate methods for purity and potency assays.

Basic Information

Product Name	4,6-Dimethyl-2(1H)-Pyrimidinone-13C,15N2 Hydrochloride
CAS No.	1329509-46-7
Molecular Formula	C5[13C]H9N[15N]2O • HCl
Molecular Weight	Contact for details
Synonyms	2-Hydroxy-4,6-dimethylpyrimidine-13C,15N2 Hydrochloride
4,6-Dimethyl-2-pyrimidinol-13C,15N2 Hydrochloride
4,6-Dimethyl-2-hydroxypyrimidine-13C,15N2 Hydrochloride
4,6-Dimethylpyrimidin-2(1H)-one-13C,15N2 Hydrochloride
4,6-Dimethyl-2(1H)-pyrimidinone-13C,15N2 HCl
Isotopically Labeled Pyrimidinone Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4,6-Dimethyl-2(1H)-Pyrimidinone-13C,15N2 Hydrochloride is manufactured and analyzed under strict quality systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for isotopic purity, chemical purity, and stability. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay, isotopic enrichment, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C; ≥ 99 atom % 15N
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.