Description

3-[2-Fluoro-5-Methyl-4-(Trifluoromethyl)Phenyl]Propionicacid is a high-value fluorinated aromatic propionic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to construct novel active ingredients with improved efficacy and patent life.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drugs, particularly in oncology, CNS, and inflammatory disease research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine motifs enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring structure-activity relationships (SAR) and creating proprietary compound libraries.
• Custom Synthesis & Contract Manufacturing: A pivotal substrate for custom synthesis houses producing tailored intermediates for client-specific projects.

Basic Information

Item	Detail
Product Name	3-[2-Fluoro-5-Methyl-4-(Trifluoromethyl)Phenyl]Propionicacid
CAS No.	1323966-25-1
Molecular Formula	C11H8F4O2
Molecular Weight	248.17 g/mol
Synonyms	2-Fluoro-5-methyl-4-(trifluoromethyl)benzenepropanoic acid; 3-(2-Fluoro-5-methyl-4-(trifluoromethyl)phenyl)propanoic acid; 2-Fluoro-α,α,α-trimethyl-m-toluicpropionic acid derivative; 1323966-25-1; FMPTPA; 4-(Trifluoromethyl)-2-fluoro-5-methylphenylpropionic acid
EINECS	Contact for details

Quality Control

Every batch of 3-[2-Fluoro-5-Methyl-4-(Trifluoromethyl)Phenyl]Propionicacid is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure the material meets the precise requirements of your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment and are available upon request for evaluation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.