Description

2-Bromo-3-Fluoro-6-Methoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging the fluorine and bromine substituents for enhanced bioactivity and stability.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where the methoxy and halogen groups tune electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Item	Details
Product Name	2-Bromo-3-Fluoro-6-Methoxyphenylboronic Acid
CAS No.	1315339-47-9
Molecular Formula	C7H7BBrFO3
Molecular Weight	247.85 g/mol
Synonyms	(2-Bromo-3-fluoro-6-methoxyphenyl)boronic acid; 2-Bromo-3-fluoro-6-methoxybenzeneboronic acid; 2-Bromo-3-fluoro-6-methoxy-phenylboronic acid; Boronic acid, B-(2-bromo-3-fluoro-6-methoxyphenyl)-; 1315339-47-9; 2-Br-3-F-6-MeO-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoro-6-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.