Description

Ricinine-D3 is a stable isotope-labeled analog of the alkaloid ricinine, specifically deuterated at three positions. This compound is an essential internal standard for the accurate quantification of ricinine in complex matrices, providing superior precision and reliability in analytical workflows. It is primarily utilized by analytical laboratories, forensic toxicologists, and researchers in food safety, clinical diagnostics, and environmental monitoring who require definitive identification and measurement of this specific biomarker.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterated internal standard in LC-MS/MS and GC-MS methods for the precise quantification of ricinine, correcting for matrix effects and instrument variability.
• Forensic Toxicology & Clinical Analysis: Critical for confirming exposure to ricin or castor bean products in biological samples (e.g., blood, urine) with high specificity and sensitivity.
• Food & Agricultural Safety Testing: Enables accurate monitoring of ricinine contamination in food products, animal feed, and agricultural commodities.
• Environmental & Biothreat Detection: Supports the development and validation of robust analytical methods for detecting ricinine in environmental samples as a marker for potential security threats.
• Metabolic & Pharmacokinetic Studies: Employed in research to trace the metabolism, distribution, and clearance of ricinine and related compounds in vivo.
• Method Development & Validation: Serves as a key reference material for developing, optimizing, and validating new analytical procedures in compliance with regulatory guidelines.
• Quality Control & Reference Standards: Used by manufacturers of diagnostic kits and certified reference materials to ensure batch-to-batch consistency and accuracy.

Basic Information

Product Name	Ricinine-D3
CAS No.	1313734-77-8
Molecular Formula	C8H5D3N2O2
Molecular Weight	167.18 g/mol
Synonyms	Ricinine (methyl-D3); 3-Cyano-4-methoxy-1-methyl-2(1H)-pyridinone-D3; 1-Methyl-3-cyano-4-methoxy-2(1H)-pyridinone-D3; 4-Methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile-D3; 1-Methyl-4-methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile-D3; Deuterated Ricinine (d3); Ricinine Internal Standard (d3)
EINECS	Contact for details

Quality Control

Every batch of Ricinine-D3 is manufactured and analyzed under strict quality systems to ensure the highest standards of isotopic purity, chemical purity, and stability. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with industry standards for certified reference materials. Certificates of Analysis (COA) detailing batch-specific results for identity, purity (HPLC), isotopic enrichment (NMR/MS), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive). For long-term storage, consider storing under inert atmosphere in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.